New method enables sequencing of fetal genomes using only maternal blood sample
Stanford School of Medicine | July 4, 2012 | By Krista Conger
Researchers at Stanford University have for the first time sequenced the genome of an unborn baby using only a blood sample from the mother.
The findings from the new approach, published July 4 in Nature, are related to research that was reported a month ago from the University of Washington. That research used a technique previously developed at Stanford to sequence a fetal genome using a blood sample from the mother, plus DNA samples from both the mother and father.
The whole genome sequencing in the new Stanford study, however, did not require DNA from the father — a significant advantage when a child’s true paternity may not be known (a situation estimated to affect as many as one in 10 births in this country) or…
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